Overview

RAD-140 delivers a 90:1 anabolic-to-androgenic ratio — more anabolic than testosterone with dramatically fewer side effects. Produces dry, hard, vascular gains with zero water retention.

Key Benefits

• 20–30%+ strength increase within 3–4 weeks
• 6–10 lbs lean, dry muscle gains per cycle
• Zero water retention — every pound is real muscle
• Enhanced mental focus and gym aggression
• Pronounced vascularity and muscle hardness

Best Time to Take

Morning — RAD-140 can be mildly stimulating. Morning dosing aligns peak blood levels with your training window.

Stack Best With

• Cardarine GW-501516 — adds endurance + fat oxidation
• MK-677 Ibutamoren — enhances recovery, sleep and GH pulse
• LGD-4033 — maximum mass building (advanced users only)

Week-by-Week

PCT Required

Overview

The most studied SARM in existence. A Phase II randomized controlled trial confirmed significant lean body mass improvements and physical function gains with excellent tolerability.

Key Benefits

• 6–10 lbs of lean muscle in 8 weeks
• Preserve 100% of muscle mass during calorie deficits
• Strengthens joints, tendons and connective tissue
• Rapid recovery — reduced soreness between sessions
• Well-tolerated by both men and women

Best Time to Take

Morning with food — once daily dosing is sufficient due to 24-hour half-life.

Stack Best With

• Cardarine — the definitive beginner cutting stack
• MK-677 — improved overnight recovery and sleep quality
• LGD-4033 — more aggressive bulking (intermediate users)

Week-by-Week

PCT

Under 25mg for 8 weeks or less — PCT often optional. Longer cycles benefit from Nolvadex 20/20/10/10mg for 4 weeks.

Overview

The most potent SARM for raw muscle mass — approximately 10 times more anabolic than Ostarine. The only SARM with a published randomized, double-blind, placebo-controlled Phase I trial confirming significant lean mass gains at just 1mg/day.

Key Benefits

• 8–12 lbs lean muscle in 8 weeks at 10mg/day
• Rapid and significant strength increases from week 2
• Pronounced muscle fullness and enhanced pumps
• Noticeably improved workout performance

Best Time to Take

Morning or evening — LGD's 24–36 hour half-life gives flexibility.

Stack Best With

• MK-677 — the #1 classic bulk combination
• Cardarine — adds endurance capacity during calorie surplus
• RAD-140 — ultimate mass stack (advanced users only)

Week-by-Week

PCT Required

Overview

Cardarine activates PPARδ — the master regulator of fat metabolism and mitochondrial biogenesis. A landmark Cell paper demonstrated it mimics exercise metabolic adaptations. Completely non-hormonal with zero effect on testosterone, LH or FSH.

Key Benefits

• 30–50%+ endurance improvement within 1–2 weeks
• Dramatically enhanced fat oxidation during exercise
• Improved HDL cholesterol — positive cardiovascular marker
• Zero testosterone suppression — zero PCT ever needed
• Can run continuously through any PCT phase

Best Time to Take

30–45 minutes before training or cardio — maximizes the endurance benefit at peak activity.

Stack Best With

• Ostarine — the definitive beginner cutting stack
• S4 Andarine — elite shredding combination
• RAD-140 — recomp powerhouse combination

Week-by-Week

Overview

S4 is the go-to SARM for achieving a competition-ready physique — extreme muscle hardening, pronounced vascularity, and accelerated fat loss while preserving every ounce of lean mass.

Key Benefits

• Extreme muscle hardening and visible striations
• Accelerated fat loss while preserving lean mass
• Pronounced vascularity and skin-tight appearance
• Maintain all muscle on the most aggressive cuts

Best Time to Take

Split into 2 doses (25mg AM / 25mg PM). Use 5 days on, 2 days off schedule — this significantly reduces the known vision side effect.

Stack Best With

• Cardarine — the ultimate shredding combination
• Yohimbine — adds stubborn fat targeting
• RAD-140 — muscle preservation during aggressive cut

Vision Side Effect

Week-by-Week

Overview

MK-677 stimulates the pituitary to release natural GH and elevates IGF-1 levels. A 2-year randomized controlled trial confirmed sustained GH elevation with excellent safety. Non-hormonal — zero effect on testosterone, LH or FSH.

Key Benefits

• GH levels increase 50–100%+ within weeks
• Dramatically improved deep sleep quality from night one
• Enhanced tissue repair and recovery between sessions
• Significantly increased appetite — ideal for bulking phases
• Zero testosterone suppression — run continuously or through PCT

Best Time to Take

30–60 minutes before sleep — amplifies the natural GH pulse during deep sleep, maximizing overnight recovery and sleep quality.

Stack Best With

• Any SARM stack — no hormonal interference whatsoever
• Continue through PCT — preserves muscle while LH/FSH recovers
• LGD-4033 — the #1 bulk stack combination

Week-by-Week

Overview

YK-11 is simultaneously a SARM and a myostatin inhibitor — it inhibits the protein that limits muscle growth AND increases follistatin, potentially allowing growth beyond your genetic ceiling. The most powerful compound in the SARM category.

Key Benefits

• Inhibits myostatin — removes the natural brake on muscle growth
• Dramatically increases follistatin levels
• Breakthrough strength gains in 4–6 weeks
• Lean, dense, quality muscle with minimal fat

Best Time to Take

Split into 2 doses — morning and early afternoon due to 6–10 hour half-life. Never take in the evening as it may disrupt sleep quality.

Stack Best With

• RAD-140 — elite power stack, maximum strength (advanced only)
• MK-677 — maximize overnight recovery during cycle

Week-by-Week

PCT & Warnings

Overview

Genetix Pharma MK-677 stimulates the natural GH and IGF-1 cascade. A 2-year randomized controlled trial confirmed sustained GH elevation with excellent tolerability. Non-hormonal — zero testosterone suppression, zero PCT required at any dose or duration.

Key Benefits

• GH levels increase 50–100%+ within weeks
• Dramatically improved deep sleep quality from night one
• Enhanced recovery — workouts feel fresh faster
• Increased appetite — use for calorie surplus phases
• Zero testosterone suppression — no PCT ever required

Best Time to Take

Before bed — amplifies the natural sleep-induced GH pulse for maximum overnight anabolic benefit.

Stack Best With

• YK-11 — the elite strength and mass combination
• RAD-140 — maximum strength with elite recovery
• Any SARM — zero hormonal conflict at any dose

Overview

Cardarine activates PPARδ, enhancing fat oxidation, mitochondrial biogenesis, and endurance capacity. A landmark paper in Cell demonstrated it effectively mimics the metabolic adaptations of chronic exercise training. Fully non-hormonal.

Key Benefits

• 30–50%+ endurance improvement within the first 1–2 weeks
• Significantly enhanced fat oxidation during training
• Improved HDL cholesterol profile
• No jitters, no crash — non-stimulant mechanism
• Compatible with any other compound — zero hormonal conflict

Best Time to Take

30–45 min pre-training for maximum endurance benefit. Once daily is sufficient.

Stack Best With

• S4 Andarine — the elite shredding combination
• Yohimbine — double fat-burning mechanism
• Any SARM — adds conditioning with zero suppression

Overview

S4 delivers the hardest, driest, most striated look of any SARM. Ideal for pre-contest preparation or anyone seeking maximum definition and vascularity.

Key Benefits

• Extreme muscle hardening, striations and definition
• Enhanced fat loss while preserving lean tissue
• Pronounced vascularity — veins visible through skin
• Maintain all muscle on aggressive calorie deficits

Best Time to Take

Split 2x daily (AM and PM). Use 5 days on, 2 days off weekly schedule.

Important Note

Overview

Yohimbine blocks alpha-2 adrenergic receptors specifically in stubborn fat cells — the adipose tissue on lower abs, love handles, and glutes that resists conventional caloric restriction.

Key Benefits

• Specifically targets lower belly, love handles and glutes
• Mobilizes free fatty acids from stubborn adipose tissue
• Mild energy enhancement without stimulant crash
• Synergistic with Cardarine for dual fat-burning pathways

Critical Rule — Fasted State Only

Best Time to Take

Morning fasted — 30 min before low-intensity cardio. Walking, elliptical or cycling at 60–65% max heart rate for 25–35 minutes is ideal.

Stack Best With

• Cardarine — complementary fat-burning mechanisms
• S4 Andarine — the complete shredding trifecta
• Ostarine — preserves muscle while both compounds burn fat

Week-by-Week

Overview

Accel Pharma Cardarine activates PPARδ — dramatically enhancing endurance capacity and fat oxidation rate. Completely non-hormonal with zero effect on testosterone. Can run through any cycle phase without hormonal conflict.

Key Benefits

• 30–50%+ endurance improvement in weeks 1–2
• Significantly enhanced fat oxidation during activity
• Improved HDL cholesterol levels
• Zero suppression — no PCT required at any dose
• Can be run through any PCT to maintain conditioning

Best Time to Take

30–45 minutes before training for peak endurance. Once daily. Works effectively fasted or fed.

Week-by-Week

Overview

Accel Pharma MK-677 stimulates the natural GH/IGF-1 axis via ghrelin receptor agonism. A 2-year RCT confirmed sustained GH elevation with excellent safety profile. Non-hormonal — zero testosterone, LH or FSH suppression at any dose.

Key Benefits

• GH levels increase 50–100%+ within weeks
• Deep sleep quality improves dramatically from night one
• Enhanced recovery — less soreness, faster session turnaround
• Significantly increased appetite for bulking phases
• Zero suppression — run through any cycle or PCT

Best Time to Take

Before sleep — amplifies the natural nocturnal GH pulse for maximum overnight recovery and sleep quality enhancement.

Week-by-Week

Overview

Accel Pharma Ligandrol is the most anabolic SARM available — approximately 10x more potent than Ostarine for raw muscle mass gain. Phase I clinical trial confirmed significant lean mass increases even at very low doses.

Key Benefits

• 8–12 lbs lean muscle in 8 weeks at 10mg/day
• Significant and rapid strength increases from week 2
• Pronounced muscle fullness and enhanced pumps
• Superior workout performance

Best Time to Take

Morning — flexible timing due to 24–36 hour half-life. Morning dosing maintains anabolic signaling throughout the training day.

Week-by-Week

PCT Required

Overview

Accel Pharma Ostarine is the most researched SARM available — supported by actual Phase II clinical data confirming lean body mass improvements with excellent tolerability. The perfect starting compound for any Canadian user beginning their SARM journey.

Key Benefits

• 6–10 lbs lean muscle in 8 weeks
• Preserves muscle mass during calorie deficits
• Strengthens joints and connective tissue
• Rapid recovery between training sessions
• Suitable for men and women at appropriate doses

Best Time to Take

Morning with food — once daily, consistent timing for stable blood levels throughout the cycle.

Week-by-Week

Overview

Accel Pharma RAD-140 carries a 90:1 anabolic-to-androgenic ratio — producing more anabolic effect than testosterone with dramatically fewer androgenic side effects. The strongest available SARM for strength and lean mass gains.

Key Benefits

• 20–30%+ strength increase within 3–4 weeks
• 6–10 lbs lean, dry muscle gains per cycle
• Zero water retention — pure quality muscle
• Enhanced mental focus, drive and gym aggression

Best Time to Take

Morning — aligns peak blood levels with your training window. RAD-140's mild stimulating effect is best utilized during the day.

Week-by-Week

PCT Required

Overview

HCG stimulates the Leydig cells of the testes to produce testosterone, effectively restarting natural testosterone production after suppressive SARM or steroid cycles. Prevents testicular atrophy and dramatically speeds HPTA recovery.

Key Benefits

• Prevents testicular atrophy during and after cycles
• Kickstarts natural testosterone production
• Maintains fertility and spermatogenesis
• Dramatically speeds HPTA recovery timeline

Protocol

During heavy cycle: 250 IU 2–3x/week to prevent atrophy

Post-cycle bridge: 500 IU every other day for 2–3 weeks before starting Nolvadex/Clomid PCT

Reconstitution

Mix lyophilized powder with bacteriostatic water. Use insulin syringe for subcutaneous injection. Refrigerate after reconstitution. Use within 30 days of mixing.

Important Note